Shiseido Uplifting and Firming Advanced Cream is an age-defying expert solution designed to combat deep wrinkles, sagging, and dark spots. This advanced cream, powered by Shiseido’s patented SafflowerRED™ and ReneuraRED Technology™, helps activate skin’s self-regeneration*, offering a +35% more lifted, firmer, and brighter look in only 1 week(1) – with visible and lasting results. With a unique, soothing, and smoothing texture and the elegant fragrance of Japanese orchid, it provides both luxurious care and clinically proven results – and it’s now 4 times more efficient than before(2). The cream is dermatologist-tested, non-comedogenic, and now available as a refill that reduces plastic waste by up to 79%, compared to the original cream. -Targets deep wrinkles, sagging, and dark spots -Features patented technology -Promotes firmer and brighter skin -Refill available FAST & CLINICALLY PROVEN BENEFITS - In only 4h: +43 % more hydrated skin(3) - In just 1 week: +35 % more lifted, firmer, and brighter look(1) - After 8 weeks: +53 % more lifted, firmer, and brighter look(1) WOMEN APPROVED - 98 % feel skin firmness is enhanced(4) - 97 % feel skin looks lifted(4) - 94 % feel skin looks bright(4) - 98 % feel skin is fully moisturized(4) (1)Self-scoring by 110 women (2)Clinical scoring on firmness and brightness – 35 women for Vital Perfection Uplifting and Firming Cream and 33 women for Advanced Cream (3)Instrumental test on 27 women (4)Consumer test with 110 volunteers. % after 8 weeks *In-vitro testUse:Apply each morning and evening, after serum, and before eye cream. Take two pearl-sized amounts with the spatula. With a fingertip, dot evenly onto five areas (each cheek, forehead, nose, and chin) and spread out smoothly. Shiseido Vital Perfection Advanced Cream Refill 50 ml